Key Outcomes

>200,000

hours reduction in manual effort

>$10M

reduction in COGS through AI-driven planning and material usage

2,200

hours of cost avoidance at one site

Executive Summary

The client, a US$45 billion global biopharmaceutical enterprise founded in 1781, has a presence in around 80 countries, with 40 new clinical stage assets, 70 brands, over 25 manufacturing sites and 200+ partnerships that help bring innovation to patients. The entire enterprise was run in stand-alone silos with manual processes and fragmented data, and a multi-year effort to modernize the digital core had not improved business process efficiency or produced better insights.

Altimetrik digitized enterprise processes around a Central Business Platform and built the Agile Operating System (AOS) for tiered, visual communication from the shop floor to leadership. The result: over 200,000 hours of manual effort removed, more than $10 million in COGS reduction through AI-driven planning and material usage, and permanent digital methodologies and mindsets.

Client Snapshot

Industry
Life Sciences · Pharmaceuticals
Client Profile
US$45 billion global biopharmaceutical enterprise founded in 1781, present in around 80 countries with 40 new clinical stage assets, 70 brands, over 25 manufacturing sites and 200+ partnerships
Business Focus
Central Business Platform, enterprise process digitization, manufacturing, supply chain and quality visibility, tiered visual communication, pharmacovigilance

Business Challenge

The entire enterprise ran in stand-alone silos with manual processes and fragmented data. The lack of digitization across enterprise processes hindered the client’s ability to evolve into a modern, data-driven, autonomous enterprise, to equip Global Manufacturing, Supply Chain and Quality operations with predictive insights, and to monitor enterprise-wide process metrics.

It also limited the use of real-time connected insights, collaboration across teams and partners, cost savings and the speed with which the organization could deliver solutions to problems.

Why It Mattered

In the pharma industry, effective communication between shifts on the shop floor, across functional areas and with management is critical to maintaining product quality, reducing production errors, meeting compliance requirements and reducing turnaround time. The existing communication model lacked standard tools.

Solution

To address the challenges, the client needed to digitize a range of processes and functions around a Central Business Platform. The processes and functions that had to be transformed included:

  • The ability to view and monitor end-to-end manufacturing processes
  • Material lookup, to evaluate usage of banned materials
  • Disposition of production materials and ingredients and finished products
  • Enterprise Risk Management, to identify potential risks across the organization
  • Using visual aids to manage tier meetings and follow-up action
  • Platform features and capabilities, to frame applications for access control, notifications, CI/CD and more

Key objectives of the Central Business Platform

  • Enhanced Visibility: enterprise-wide visibility into key processes and metrics
  • Process Digitization: better collaboration, enhanced visibility and cost savings
  • Operations Optimization: automation, operational performance, quality of service and sustainable growth
  • Leading Edge Capabilities: more fitting, dependable and faster solutions to new and old problems

The Central Business Platform digitized and addressed five areas of the enterprise.

The existing communication model was complicated further by custom solutions across groups, which did not provide a consistent view across tiers. Manual systems were slow, operated in an unstructured hierarchy and often resulted in inconsistent interpretation of the charts. One of the products built under the platform umbrella, the Agile Operating System (AOS), enabled tiered communication and accountability from the shop floor to the GMSGQ leadership team using a visual system, providing access to real-time data aggregated across functions and shifts so leadership and teams across five tiers could pursue priorities and solve problems collaboratively.

Business Outcomes

Visibility across operations

  • View, manage and identify bottlenecks in the manufacturing, disposition and shipping processes
  • Stockouts prevented across the supply chain

Decision support

  • Risk analysis and decision support dashboard to identify, analyze and focus on risks, reduce costs and create more value for stakeholders
  • Search functionality to evaluate potential usage bans of materials, and improved pharmacovigilance and adverse event monitoring

Collaboration and scale

  • Visual tools to run tier meetings and follow-up action across operational units and sites, with an estimated cost avoidance of up to 2,200 hours at one site
  • Platform features such as frame application, access control and notifications, and capabilities including CI/CD and architecture

Altimetrik Advantage

The Central Business Platform and the AOS together delivered an end-to-end digital solution that promoted cross-functional collaboration between the client’s product teams, Biologics, OESSM and Plasma, and Supply Chain, Quality, SBE and DD&T.

The client is now a modern, agile, self-driven digital enterprise, with permanent digital methodologies and mindsets created along the way.